Washington UniversitySchool of Medicine
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Fred Prior

Fred Prior

Director ERL, CHPC, CBMI; Assoc. Prof. Radiology

Office: East Building 3355
Tel: (314)747-0331
Fax: (314)362-6971



B.A., Chemistry, Case Western Reserve University - 1974
M.A., Anthropology, Case Western Reserve University - 1976
M.S., Biomedical Engineering, Case Western Reserve University - 1984
Ph.D., Computer Science, Illinois Institute of Technology - 1992


Fred Prior, Ph.D. (CS), MS (BME), MA (Anthro), BA (Chem) is the Director of the Electronic Radiology Laboratory of the Mallinckrodt Institute of Radiology, and a Research Associate Professor of Radiology, Washington University in Saint Louis School of Medicine. Dr. Prior has over 30 years of R&D experience focused mostly on the design of advanced medical information management and communication technologies. He has worked in a variety of R&D environments ranging from Silicon Valley startups to major multi-national corporations in the US and Europe. He has held senior management positions with Imatron, Siemens Medical Systems, Philips Medical System, Cemax-Icon and Eastman Kodak and was formerly a member of the faculty of the departments of Radiology, Neuroscience and Bioengineering at Penn State University College of Medicine.

Research Interests

Dr. Prior's research interests reflect those of the lab: research informatics and quantitative imaging. He is the PI for The Cancer Imaging Archive (TCIA) project and actively engaged in the Human Connectome Project where he is workong on MEG derived dynamic connectomics. Dr. Prior has a long standing interest in quantitative image feature extraction, data mining and EEG/MEG source space imaging.

Affiliations/Professional Studies

Institute of Electrical and Electronics Engineers (IEEE) - Senior Member

Organization for Human Brain Mapping -  Member

IEEE Journal of Biomedical and Health Informatics - Associate Editor

Computerized Medical Imaging and Graphics - Reviewing Editor

Select Publications

  1. Prior FW, Nabijee KH. Information Management for Data Retrieval in a Picture Archive and Communication System.  J Digit Imaging. 1989; 2(3):170-176.
  2. Prior FW, Specifying DICOM Compliance for Modality Interfaces. RadioGraphics. 1993; 13:1381-1388, 1993.
  3. Bidgood WD, Horii SC, Prior FW, Van Syckle DE. Understanding and Using DICOM, the Medical Image Communication Standard. JAMIA. 1997; 4:199-212.
  4. Coates TD, Larson-Prior L, Wolpert S, Prior FW. Classification of Simple Stimuli Based on Detected Nerve Activity. IEEE Eng Med Biol. 2003; 22(1):64-76. PMID: 12683065
  5. Falk D, Hildeboldt C, Smith K, Morwood MJ, Sutikna T, Brown P, Brunsden B, Prior FW.  The Brain of LB1, Homo floresiensis.  Science 2005 308(5719):242-5. PMID: 15749690
  6. Falk D, Hildeboldt C, Smith K, Morwood MJ, Sutikna T, Saptomo E, Imhof H, Seidler H, Prior FW.  Brain Shape in Human Microcephalics and Homo floresiensis.  PNAS 2007; 104(7):2513-2518. PMCID: PMC1892980
  7. Prior F, Erickson B, Tarbox L. Open Source Software Projects of the caBIG™ In Vivo Imaging Workspace Software Special Interest Group.  Journal of Digital Imaging, 2007; 20(supl 1):94-100, doi: 10.1007/s10278-007-9061-4. PMCID: PMC2039820
  8. Vendt B, McKinstry R, Ball, W Kraut M, Prior F, DeBaun M. Silent Cerebral Infarct Transfusion (SIT) Trial Imaging Core: Application of Novel Imaging Information Technology for Rapid and Central Review of MRI of the Brain.  Journal of Digital Imaging, 2009; 22(3):326-343, DOI: 10.1007/s10278-008-9114-3. PMCID: PMC2801625
  9. Erinjeri  JP, Picus D, Prior F, Rubin D,  Koppel P, Development of a Google-Based Search Engine for Data Mining Radiology Reports.  Journal of Digital Imaging, 2009; 22(4):348:356, doi: 10.1007/s10278-008-9110-7. PMID: 18392657
  10. Hastings M,  Gelber J, Commean P, Prior F, Sinacore D, Bone Mineral Density of the Tarsals and Metatarsals with Reloading.  Physical Therapy, 2008; 88(6):1-13, doi: 10.2522/ptj.20070226. PMCID: PMC2409979
  11. Clark K, Gierada D, Marquez G, Moore S, Maffitt D, Moulton J, Wolfsberger M, Koppel P, Phillips S, Prior F, Collecting 48,000 CT Exams for the Lung Screening Study of the National Lung Screening Trial. Journal of Digital Imaging, 2009; 22(6):667-680, DOI 10.1007/s10278-008-9145-9. PMID: 18777192
  12. Prior F,  Brunsden B,  Hildebolt C, Nolan T, Pringle M, Vaishnavi SN, Larson-Prior, L, Facial Recognition from Volume Rendered Magnetic Resonance Imaging Data. IEEE Trans. Inf. Tech. Biomed, 2009; 13(1):5-9. PMID: 19129018
  13. Prior F, Medical Knowledge Discovery and Management. Mil Med 2009; 174 (5) (Suppl): 21-26. PMID: 19562958
  14. Falk D, Hildeboldt C, Smith K, Jungers W, Larson S, Morwood M, Sutikna T, Jatmiko, Saptomo E, Prior F.  The Type Specimen (LB1) of Homo floresiensis Did Not Have Laron Syndrome. Am J Phy Anthro. 2009; 140(1):52-63. DOI: 10.1002/ajpa.21035. PMID: 19294744
  15. Larson-Prior L, Zempel J, Nolan T, Prior F, Snyder A, Raichle M, Cortical network functional connectivity in the descent to sleep. PNAS 2009; 106(11): 4489-4494, doi: 10.1073/pnas.0900924106. PMCID: PMC2657465
  16. Falk D, Hildebolt C, Smith K, Morwood M.J., Sutikna T, Jatmiko, Saptomo E, Prior F, LB1's virtual endocast, microcephaly, and hominin brain evolution, Journal of Human Evolution, 2009; 57(5):597-607, doi: 10.1016/j.jhevol.2008.10.008. PMID: 19254807 
  17. Cholleti S, Goldman S, Blum A, Politte D, Don S, Smith K, Prior F, VERITAS: Combining Expert Opinions Without Labeled Data.  International Journal on Artificial Intelligence Tools, 2009; 18(5):633-651.
  18. Chen J, Wong S, Chang J, Chung P, Li H, Koc U, Prior F, Newcomb R.  Wake-up Call for the Engineering and Biomedical Science Communities - Major Challenges in Biomarker Development and Application, IEEE Circuits and Systems, 2009; 9(2):69-77, doi:10.1109/MCAS.2009.932557.
  19. Prior F, Commean P, Ju T, Hastings M, Hildebolt C, Sinacore D. Developing a Biomarker for Neuropathic Arthropathy in Diabetic Patients.  IEEE/NIH Life Science Systems and Applications Workshop, 2007; 13-16. IEEE Xplore DOI 10.1109/LSSA.2007.4400873
  20. Liu L, Raber D, Nopachai D, Commean P, Sinacore D, Prior F, Pless R, Ju T. Interactive Separation of Segmented Bones in CT Volumes using Graph Cut,  Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008 2008;52411(Pt 1):296-304. PMID: 18979760
  21. Prior F, Ingeholm M, Levine B, Tarbox L.  Potential Impact of HITECH Security Regulations on Medical Imaging.  IEEE EMBS Conf. 2009, 2157-2160. IEEE Xplore, DOI 10.1109/IEMBS.2009.5332507. PMID: 19963534
  22. Philbin J, Prior F., Nagy P. Will the next generation of PACS be sitting on a cloud? Journal of Digital Imaging, 2010, DOI: 10.1007/s10278-010-9331-4.
  23. Politte D, Prior F, Ponton C, Nolan T, Larson-Prior L, Sources of non-physiologic noise in simultaneous EEG-fMRI data: a phantom study. IEEE EMBS Conf. 2010, 5129-5132. IEEE Xplore, DOI 10.1109/IEMBS.2010.5626168. PMID: 21095809.
  24. Rhodes C, Moore S, Clark K, Maffitt D, Perry J, Handzel T, Prior F, Regulatory Compliance Requirements for an Open Source Electronic Image Trial Management System. IEEE EMBS Conf. 2010, 3475-3478. IEEE Xplore, DOI 10.1109/IEMBS.2010.5627838. PMID: 21097264
  25. Kenneth Clark, Bruce Vendt, Kirk Smith, John Freymann, Justin Kirby, Paul Koppel, Stephen Moore, Stanley Phillips, David Maffitt, Michael Pringle, Lawrence Tarbox and Fred Prior , ”The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository”, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057.

 For a complete bibliography consult my Google Scholar Profile